• Email Us: [email protected]
  • Contact Us: +1 718 874 1545
  • Skip to main content
  • Skip to primary sidebar

Medical Market Report

  • Home
  • All Reports
  • About Us
  • Contact Us

Measurable Brain Changes Following Cognitive Behavioral Therapy Identified For The First Time

August 28, 2025 by Deborah Bloomfield

You’ll sometimes hear psychotherapy referred to as “talking therapy,” and it’s not entirely wrong. Some routes of treatment, including cognitive behavioral therapy (CBT), can involve a lot of talking as therapists work with clients to try and question negative patterns of thinking and pave the way for a fresh outlook. Thing is, people aren’t always convinced that it can be as effective as “hard” approaches like medicine, but now, scientists have found evidence of physical and measurable changes in the brain following CBT.

The rest of this article is behind a paywall. Please sign in or subscribe to access the full content.

The study looked at the brains of 30 people diagnosed with acute depression using structural magnetic resonance imaging (MRI). They took scans both before and after 20 sessions of cognitive behavioral therapy and compared them to see if there were any differences.

The fact that it has such a strong positive effect on the brain structure, specifically the gray matter, was a pleasant surprise in this extent

Professor Ronny Redlich

The scans revealed a significant increase in the volume of gray matter in the left amygdala and right anterior hippocampus. The researchers also conducted clinical interviews, and found that the people who showed the greatest increase in gray matter in the amygdala also showed a stronger reduction in emotional dysregulation. In total, they concluded that 19 of the 30 participants who started out with acute depression showed hardly any symptoms following therapy.

The merits of CBT have long been recognized, but this study marks the first time that a measurable and reliable biomarker has been identified to observe the physical effect psychotherapy has on brain structure. That’s not to say that other therapies, such as medicine, are better or worse, but it adds further support to the idea that there’s a lot more to psychotherapy than just talking.

“The study is of high quality and the results are statistically very robust,” said study author Professor Ronny Redlich, who heads the Department of Biological and Clinical Psychology at Martin Luther University Halle-Wittenberg (MLU). “The fact that psychotherapy changes brain function is still easy for most people to understand. However, the fact that it has such a strong positive effect on the brain structure, specifically the gray matter, was a pleasant surprise in this extent.”

Psychotherapy is not just a bit of talking, but rather a structured and effective treatment for mental disorders

Professor Ronny Redlich

“This is generally a milestone: psychotherapy is not only mental, but also affects our brain. And it does so very strongly. Although we did not directly compare it with psychotropic drugs, I believe the effects are probably similarly strong.”

The team hopes the findings will be able to settle any lingering misconceptions about the efficacy of psychotherapy and CBT, and perhaps contribute to a general shift in the way we think about mental health conditions, why they occur, and what we can do about it.

“It’s only a small step, but I think the potential for a more forward-looking and objective view of psychotherapy among the general population is huge: psychotherapy is not just a bit of talking, but rather a structured and effective treatment for mental disorders,” Redlich told IFLScience. 

“Mental disorders are not a ‘weakness’ of the person, but can also be attributed to physical changes, especially in the brain. Psychotherapy is able to ‘repair’ these brain connections so that, in best case scenario, the patient feels better afterwards. I think this perspective helps many patients, takes the blame off the person themselves, and destigmatizes both mental disorders and psychotherapy.”

The study is published in the journal Translational Psychiatry.

Deborah Bloomfield
Deborah Bloomfield

Related posts:

  1. Matillion raises $150M at a $1.5B valuation for its low-code approach to integrating disparate data sources
  2. There Are Ripples At The Boundary Of Interstellar Space
  3. Atomic Bomb Tests And The Dawn Of The Bikini, 1946 Was A Strange Summer
  4. 2,000-Year-Old Leather Shoe Reveals Some Roman Soldiers Had Massive Feet

Source Link: Measurable Brain Changes Following Cognitive Behavioral Therapy Identified For The First Time

Filed Under: News

Primary Sidebar

  • The Bizarre 1997 Experiment That Made A Frog Levitate
  • There’s A Very Good Reason Why October 1582 On Your Phone Is Missing 10 Days
  • Skynet-1A: Military Spacecraft Launched 56 Years Ago Has Been Moved By Persons Unknown
  • There’s A Simple Solution To Helping Avoid Erectile Dysfunction (But You’re Not Going To Like It)
  • Interstellar Object 3I/ATLAS May Be 10 Billion Years Old, This Rare Spider Is Half-Female, Half-Male Split Down The Middle, And Much More This Week
  • Why Do Trains Not Have Seatbelts? It’s Probably Not What You Think
  • World’s Driest Hot Desert Just Burst Into A Rare And Fleeting Desert Bloom
  • Theoretical Dark Matter Infernos Could Melt The Earth’s Core, Turning It Liquid
  • North America’s Largest Mammal Once Numbered 60 Million – Then Humans Nearly Drove It To Extinction
  • North America’s Largest Ever Land Animal Was A 21-Meter-Long Titan
  • A Two-Headed Fossil, 50/50 Spider, And World-First Butt Drag
  • Interstellar Comet 3I/ATLAS Is Losing Buckets Of Water Every Second – And It’s Got Cyanide
  • “A Historic Shift”: Renewables Generated More Power Than Coal Globally For First Time
  • The World’s Oldest Known Snake In Captivity Became A Mom At 62 – No Dad Required
  • Biggest Ocean Current On Earth Is Set To Shift, Spelling Huge Changes For Ecosystems
  • Why Are The Continents All Bunched Up On One Side Of The Planet?
  • Why Can’t We Reach Absolute Zero?
  • “We Were Onto Something”: Highest Resolution Radio Arc Shows The Lowest Mass Dark Object Yet
  • How Headsets Made For Cyclists Are Giving Hearing And Hope To Kids With Glue Ear
  • It Was Thought Only One Mammal On Earth Had Iridescent Fur – Turns Out There’s More
  • Business
  • Health
  • News
  • Science
  • Technology
  • +1 718 874 1545
  • +91 78878 22626
  • [email protected]
Office Address
Prudour Pvt. Ltd. 420 Lexington Avenue Suite 300 New York City, NY 10170.

Powered by Prudour Network

Copyrights © 2025 · Medical Market Report. All Rights Reserved.

Go to mobile version