• Email Us: [email protected]
  • Contact Us: +1 718 874 1545
  • Skip to main content
  • Skip to primary sidebar

Medical Market Report

  • Home
  • All Reports
  • About Us
  • Contact Us

With Long Life Comes Tiny Testicles For Bowhead Whales

September 27, 2022 by Deborah Bloomfield

Living forever can get messy in the context of cancer as the longer an organism is on this Earth, generally speaking, the higher its risk of developing a genetic mutation that can lead to disease. Some plucky animals, like the bowhead whale, have adapted to overcome this, becoming one of the longest living species on Earth, but it seems the evolutionary quirk that enabled them to do this may have come with some side effects including unusually small testicles.

Bowhead whales (Balaena mysticetus) can live to be 211 years old and beyond, and a new preprint paper has found that they can enjoy their old age without the Big C looming over them as they have a unique type of gene duplication that slows the division of cells. It’s likely that this genetic quirk is one of many that contributes toward their longevity, but researchers on a new paper think it could well be the most significant.

Advertisement

Peto’s Paradox is the name given to the perplexing phenomenon we observe when animals, like whales and elephants, live to an unusually great age and don’t get cancer. Some estimates put humans’ risk of developing cancer throughout their lifetime at one in two, making the Peto’s Paradox an intriguing source of envy for our species.

Using evolutionary genomics and comparative experimental biology, a research team working at the University of Buffalo in New York decided to dive into the longevity of bowhead whales. Their analyses revealed that they are able to lower the risk of tumor production by slowing cell division, giving each cell more time to fix any damage it incurred before it churns outs more cells that are similarly genetically compromised.

A gene called CDKN2C is to thank for the insurance, and it likely emerged around 4 to 5 million years ago after bowhead whales diverged from right whales. However, where CDKN2C giveth it apparently also taketh away: the gene duplication appears to have a negative effect on male fertility as it influences sperm production and shrinks testicle size.

Advertisement

This is apparently evident in bowhead whales, whose testicles weigh just 200 kilograms (441 pounds). Probably sounds intimidating to the average male human (as it should), but it sounds an awful lot smaller in the context that the testicles of right whales (their close relatives) weigh in at around 1,000 kilograms (2,205 pounds).

“Bowhead whales are an excellent model system in which to explore the evolution of long lifespans because they are closely related to species with much shorter lifespans,” concluded the study authors.

“Our experimental data indicate that CDKN2CRTG may regulate the cell cycle and contribute to enhanced DNA damage repair. These data suggest that Bowhead whales evolved their extremely long lifespans at least in part through duplication of the CDKN2C gene, which may reduce their lifetime risk of developing cancer.”

Advertisement

The preprint was published in bioRxiv.

Deborah Bloomfield
Deborah Bloomfield

Related posts:

  1. The Marvel Unlimited comics app just got a major overhaul
  2. French business activity weaker than expected in September – flash PMI
  3. Migration not the solution to EU’s population challenge -CEE leaders
  4. Hundreds throng passport office in Afghan capital

Source Link: With Long Life Comes Tiny Testicles For Bowhead Whales

Filed Under: News

Primary Sidebar

  • Unethical Experiments: When Scientists Really Should Have Stopped What They Were Doing Immediately
  • The First Humans Were Hunted By Leopards And Weren’t The Apex Predators We Thought They Were
  • Earth’s Passage Through The Galaxy Might Be Written In Its Rocks
  • What Is An Einstein Cross – And Why Is The Latest One Such A Unique Find?
  • If We Found Life On Mars, What Would That Mean For The Fermi Paradox And The Great Filter?
  • The Longest Living Mammals Are Giants That Live Up To 200 Years In The Icy Arctic
  • Entirely New Virus Detected In Bat Urine, And It’s Only The 4th Of Its Kind Ever Isolated
  • The First Ever Full Asteroid History: From Its Doomed Discovery To Collecting Its Meteorites
  • World’s Oldest Pachycephalosaur Fossil Pushes Back These Dinosaurs’ Emergence By 15 Million Years
  • The Hole In The Ozone Layer Is Healing And On Track For Full Recovery In The 21st Century, Thanks To Science
  • First Sweet Potato Genome Reveals They’re Hybrids With A Puzzling Past And 6 Sets Of Chromosomes
  • Why Is The Top Of Canada So Sparsely Populated? Meet The “Canadian Shield”
  • Humans Are In The Middle Of “A Great Evolutionary Transition”, New Paper Claims
  • Why Do Some Toilets Have Two Flush Buttons?
  • 130-Year-Old Butter Additive Discovered In Danish Basement Contains Bacteria From The 1890s
  • Prehistoric Humans Made Necklaces From Marine Mollusk Fossils 20,000 Years Ago
  • Zond 5: In 1968 Two Soviet Steppe Tortoises Beat Humans To Orbiting Around The Moon
  • Why Cats Adapted This Defense Mechanism From Snakes
  • Mother Orca Seen Carrying Dead Calf Once Again On Washington Coast
  • A Busy Spider Season Is Brewing: Why This Fall Could See A Boom Of Arachnid Activity
  • Business
  • Health
  • News
  • Science
  • Technology
  • +1 718 874 1545
  • +91 78878 22626
  • [email protected]
Office Address
Prudour Pvt. Ltd. 420 Lexington Avenue Suite 300 New York City, NY 10170.

Powered by Prudour Network

Copyrights © 2025 · Medical Market Report. All Rights Reserved.

Go to mobile version