• Email Us: [email protected]
  • Contact Us: +1 718 874 1545
  • Skip to main content
  • Skip to primary sidebar

Medical Market Report

  • Home
  • All Reports
  • About Us
  • Contact Us

“It’s Alive!”: The Real (And Horrifying) Science That Inspired Mary Shelley’s Frankenstein

November 7, 2025 by Deborah Bloomfield

When I get up to stand, it doesn’t occur to me to question how I can move because, well, we’ve figured it out. But there was a time when the way our tissues and nerves produced movement was a complete mystery.

Turns out, the quest to figure such a simple thing out inspired one of the greatest gothic science fiction stories of all time: Frankenstein. Ahead of the Netflix release from director Guillermo del Toro, let’s take a look at the real science that inspired its original creator, Mary Shelley.

Luigi Galvani and “animal electricity”

Our story begins with Luigi Galvani, an Italian physician who, in the 1780s, began doing some rather eye-opening experiments with frogs. Like many scientific origin stories, what happened next exists in several versions (we like the soup story, too), but according to historians at the University of Münster, it began with a table full of frogs used for medical training.

Frogs were often used in medical training for dissections, but one day something interesting happened when one of Galvani’s assistants touched a frog’s leg with a scalpel. Another student in the room reported seeing a spark just as the scalpel reached the frog and so began Galvani’s search for “animal electricity” – a force he believed could explain how muscles move.

Frankenstein’s frogs

To test the theory, he got some more frogs. Well, half frogs, I should say. The poor amphibians were relieved of their upper bodies so that only the legs and nerves were left behind.

An illustration of how the frogs were prepared for Galvin's experiments. They are cut off at the waist so the legs are intact and associated nerves exposed

An illustration of how the frogs were prepared for Galvani’s experiments.

He then hung them from metal hooks on the iron railing of his terrace, hoping lightning might strike and set them twitching. It sounds like some pretty grim Halloween decorations, but during thunderstorms, the legs really did move.

Eventually Galvani proved that it was possible to produce the effect without lightning by connecting the nerves with two different metals that formed an electrical circuit. His theory of Galvanism was born in 1786, a breakthrough that captured the imagination of a young Mary Shelley as she penned her 1818 novel, Frankenstein.

A galvanised corpse

A great achievement for Galvani, it could be said, and if only it had stopped there. His nephew, Giovanni Aldini, decided to carry on his uncle’s legacy, and it’s here that things start to get really weird. As Dr Austin Lim writes in his book Horror On The Brain: The Neuroscience Behind Science Fiction, Aldini began testing on things much bigger than frogs.

a galvanised corpse getting out of its coffin, man looks shocked and demon goblins look on

A galvanised corpse.

Stepping out of the lab, he brought galvanism to the public in demonstrating how decapitated oxen, sheep, horses, and dogs could all be zapped into gnashing, blinking, and thrashing with a bit of electricity. Then, he took the show to the gallows.

An account of Aldini’s human experiments was shared by Professor of History at Abertyswyth University Iwan Morus in an article published to The Conversation. It reads:

“On the first application of the process to the face, the jaw of the deceased criminal began to quiver, the adjoining muscles were horribly contorted, and one eye was actually opened. In the subsequent part of the process, the right hand was raised and clenched, and the legs and thighs were set in motion.”



Hoo boy. By comparison, Guillermo del Toro’s interpretation for Netflix will be light relief.

Deborah Bloomfield
Deborah Bloomfield

Related posts:

  1. U.S. casino stocks fall with jitters over Macau regulations, COVID-19 outbreak
  2. Iran’s foreign minister says we were not first to cut ties with Saudi
  3. Bison Calf Euthanized After Tourist Handles It In Yellowstone National Park River
  4. Why Do Some Toilets Have Two Flush Buttons?

Source Link: “It’s Alive!”: The Real (And Horrifying) Science That Inspired Mary Shelley’s Frankenstein

Filed Under: News

Primary Sidebar

  • Citizen Scientists Are Helping With Rescue Efforts In Hurricane Melissa’s Aftermath – Here’s How You Can Too
  • What Is The Radio Blackout Scale And When Is It Needed?
  • “It’s Alive!”: The Real (And Horrifying) Science That Inspired Mary Shelley’s Frankenstein
  • First-Ever View Of The Sun’s Polar Magnetic Field Reveals Major Surprise
  • A Killer Whale Birth Has Been Captured On Camera In The Wild For The First Time
  • If You Shine A Light In Your Garden And See Lots Of Dots Reflected Back, We’ve Got Bad News
  • The “Sailor’s Eyeball” Blob Is One Of The Largest Single-Celled Organisms Ever Discovered
  • Icefish Live In Sub-Zero Antarctic Waters, So Why Don’t They Freeze?
  • We Finally Know What Happened To The Stone Of Destiny
  • Meet The Fishing Cat: The World’s Most Aquatic Feline Has Evolved To Master The Wetlands
  • Why Is There A Mysterious White Pyramid In Arizona?
  • Humpback Hitchhickers: Watch POV Footage Of Suckerfish Clinging To Whales As They Migrate Across Oceans
  • Oldowan Tools Saw Early Humans Through 300,000 Years Of Fire, Drought, And Shifting Climates, New Site Reveals
  • There Are Just Two Places In The World With No Speed Limits For Cars
  • Three Astronauts Are Stranded In Space Again, After Their Ride Home Was Struck By Space Junk
  • Snail Fossils Over 1 Million Years Old Show Prehistoric Snails Gave Birth to Live Young
  • “Beautiful And Interesting”: Listen To One Of The World’s Largest Living Organisms As It Eerily Rumbles
  • First-Ever Detection Of Complex Organic Molecules In Ice Outside Of The Milky Way
  • Chinese Spacecraft Around Mars Sends Back Intriguing Gif Of Interstellar Comet 3I/ATLAS
  • Are Polar Bears Dangerous? How “Bear-Dar” Can Keep Polar Bears And People Safe (And Separate)
  • Business
  • Health
  • News
  • Science
  • Technology
  • +1 718 874 1545
  • +91 78878 22626
  • [email protected]
Office Address
Prudour Pvt. Ltd. 420 Lexington Avenue Suite 300 New York City, NY 10170.

Powered by Prudour Network

Copyrights © 2025 · Medical Market Report. All Rights Reserved.

Go to mobile version